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Design, synthesis, and evaluation of 4-(substituted)phenyl-2-thioxo-3,4-dihydro-1H-chromino[4,3-d]pyrimidin-5-one and 4-(substituted)phenyl-3,4-dihydro-1H-chromino[4,3-d]pyrimidine-2,5-dione analogs as antitubercular agents

✍ Scribed by Ambre, Premlata K.; Pissurlenkar, Raghuvir R. S.; Wavhale, Ravindra D.; Shaikh, Mushtaque S.; Khedkar, Vijay M.; Wan, Baojie; Franzblau, Scott G.; Coutinho, Evans C.


Book ID
121534807
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
585 KB
Volume
23
Category
Article
ISSN
1054-2523

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✍ Thomas Brady; Khang Vu; Jack R. Barber; Shi Chung Ng; Yuefen Zhou πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 440 KB

Novel 2,3-substituted-2,4-dihydro-pyrazolo[4,3-d] pyrimidine-5,7-diones were successfully synthesized with moderate to good yields using a new synthetic approach. The structures of the regio-isomers in this series were determined by single crystal X-ray analysis and NMR spectra.