Synthesis and properties of 2-substitute
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L. M. Demina; M. Yu. Gavrilov; M. I. Vakhrin; M. E. Konshin
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Article
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1991
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Springer US
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English
โ 388 KB
Cyclization of 2- (N-acetyl-N-arylamino)nicotinonitriles in the presence of dry HCI gave 1-aryl-2-methyl-4-oxo-l,4-dihydropyrido[2,3-d]pyrimidines. It was shown that they are acylated by acetic anhydride, aroyl chlorides, and phenyl isocyanate at the methyl group and that with benzaldehyde they give