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Synthesis and physicochemical properties of new 1N o-(m- and p-) bromobenzyl substituted derivatives of 5-(aminodialkyl)methylcytosine

✍ Scribed by Dorota Prukala

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
274 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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Simple alkylation of 5‐(aminodialkyl)methylcytosine a‐d gives twelve new, potentially biologically active 1N o‐(m‐ or p‐) bromobenzyl derivatives of 5‐substituted cytosine 1‐12 with high regioselectivity. The structures of all compounds have been confirmed by elemental analysis, IR, ^1^H NMR and ^13^C NMR spectroscopic measurements.

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