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Synthesis and photophysical properties of 8-arylbutadienyl 2′-deoxyguanosines

✍ Scribed by Yoshio Saito; Makio Koda; Yuta Shinohara; Isao Saito

Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
525 KB
Volume
52
Category
Article
ISSN
0040-4039

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✦ Synopsis

We have developed novel push-pull-type 8-arylbutadienyl 2 0 -deoxyguanosine derivatives, AB G (1a) and CB G (1b). These nucleosides exhibit strong solvent polarity dependent fluorescence emission at long wavelength (ca. 490-550 nm). These environmentally sensitive fluorescent deoxyguanosines are powerful tools for structural studies of nucleic acids and also in molecular diagnostics.

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