𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Phospholipase A 2 Inhibitory Activity of Thielocin B3 Derivatives

✍ Scribed by Teshirogi, Isao; Matsutani, Shigeru; Shirahase, Kazuhiro; Fujii, Yasuhiko; Yoshida, Tadashi; Tanaka, Kazushige; Ohtani, Mitsuaki

Book ID
120426088
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
407 KB
Volume
39
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis and enzyme inhibitory activiti
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2
✍ Rut Lucas; Amalia Úbeda; Miguel PayΓ‘; Mario Alves; Esther del Olmo; JosΓ© L. LΓ³pe πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 134 KB

We have synthesised some lipidic diamines and aminoalcohols and examined their behaviour as inhibitors of secretory and cytosolic PLA2. Some structure-activity relationships considerations have been deduced. Compound 14 was a potent and selective inhibitor of cPLA2 and compound 4 showed a dual inhib