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Synthesis and pharmacological properties of TOAC-labeled angiotensin and bradykinin analogs

✍ Scribed by C.R Nakaie; E.G Silva; E.M Cilli; R Marchetto; S Schreier; T.B Paiva; A.C.M Paiva

Book ID: 117408185
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 80 KB
Volume: 23
Category: Article
ISSN: 0196-9781
DOI: 10.1016/s0196-9781(01)00580-0

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## Abstract N‐Terminally and internally labeled analogues of the hormones angiotensin (AII, DRVYIHPF) and bradykinin (BK, RPPGFSPFR) were synthesized containing the paramagnetic amino acid 2,2,6,6‐tetramethylpiperidine‐1‐oxyl‐4‐amino‐4‐carboxylic acid (TOAC). TOAC replaced Asp^1^ (TOAC^1^‐AII) and

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