A series of 1-azabicyclo[2.2.2]octan-3-one oximes and related 1-azabicyclo-[2.2.2]-octan-3-one hydroxylamines were synthesized and tested for muscarinic M3 activity. All compounds showed at least some muscarinic binding properties, however, only one member of the series demonstrated mucarinic M3 ago
Synthesis and pharmacological properties of 2-azabicyclo[2.2.2]octane derivatives representing conformational restricted isopethidine analogues
✍ Scribed by Mario Cardellini; Gian Mario Cingolani; Francesco Claudi; Ugo Gulini; Franco Cantalamessa; Fabrizio Venturi
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 437 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0223-5234
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