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Synthesis and leishmanicidal activity of quinoline–triclosan and quinoline–eugenol hybrids

✍ Scribed by Victor Arango, Jorge J. Domínguez, Wilson Cardona, Sara M. Robledo, Diana L. Muñoz, Bruno Figadere, Jairo Sáez


Book ID
118195278
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
456 KB
Volume
21
Category
Article
ISSN
1054-2523

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Synthesis of [2-13C]quinoline and [3-13C
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CIQuinoline and [3-Clquinoline were synthesised by a five-step process starting from isatin. Acetylation of isatin with acetyl chloride labelled in either the 1or 2-position, was followed by the Pfitzinger reaction to give 2-hydroxy-4-quinoline carboxylic acid labelled in the 2- or 3-position. Dec