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Synthesis and in vivo studies of the stereoisomers of N-[11C]methyl-homoepibatidine

✍ Scribed by Jörg T Patt; Jörg E Spang; Alfred Buck; Heidi Cristina; Magarete Arras; P.August Schubiger; Gerrit Westera

Book ID
117687735
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
465 KB
Volume
28
Category
Article
ISSN
0969-8051

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Synthesis of N-[11C]-methyl-L-DOPA
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✍ Dr. Andrew Horti; Hayden T. Ravert; Robert F. Dannals; Henry N. Wagner Jr. 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 409 KB

## Abstract The radiochemical synthesis of N‐[^11^C‐methyl]‐L‐DOPA was accomplished by N‐methylation of the methyl and ethyl esters of L‐N‐tert‐butyl‐oxycarbonyl‐[β‐(3,4‐dimethoxyphenyl)] alaninate with [^11^C]iodomethane using sodium hydride in tetrahydrofuran and deprotection of the N‐methyl inte