Synthesis and in vitro evaluation of 2-[
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Choong Mo Kang; Yearn Seong Choe; Kyung-Ho Jung; Joon Young Choi; Kyung-Han Lee;
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Article
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2011
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John Wiley and Sons
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French
⚖ 339 KB
In the present study, 2‐methoxyestradiol‐3,17β‐__O__,__O__‐bissulfamate (1), a known angiogenesis inhibitor, was prepared in a radiolabeled form by ^11^C‐methylation of 2‐hydroxyestradiol‐3,17β‐__O,O__‐bis(__N__‐trityl)sulfamate (6) followed by detritylation. Synthesis of precursor 6 required a rath