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Synthesis and in vivo evaluation of [18F]-N-(p-Nitrobenzyl)spiperone ([18F]PNBS) in rats

✍ Scribed by Mach, Robert H.; Nowak, Peggy A.; Moroney, Deborah A.; Morton, Thomas E.; Jackson, Joseph R.; Ehrenkaufer, Richard L.E.

Book ID
123285781
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
1003 KB
Volume
20
Category
Article
ISSN
0969-8051

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✍ G. Bormans; M. R. Kilbourn 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 373 KB

## Abstract We have synthesized the fluorine‐18 labeled derivative of __N__‐__tert__‐butyl‐α‐phenylnitrone (PBN), a free radical spin trapping agent widely used with electron spin resonance (ESR). __N__‐__tert__‐Butyl‐α‐(4‐[^18^F]fluorophenyl)‐nitrone ([^18^F]FPBN) could be prepared with low radioc