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Synthesis and in vivo evaluation of [11C]CGP62349, a new GABAB receptor antagonist

✍ Scribed by S Todde; R.M Moresco; W Fröstl; P Stampf; M Matarrese; A Carpinelli; F Magni; M Galli Kienle; F Fazio

Book ID
117687622
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
476 KB
Volume
27
Category
Article
ISSN
0969-8051

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Synthesis and evaluation of [11C]RU40555
Synthesis and evaluation of [11C]RU40555, a selective glucocorticoid receptor antagonist
✍ Takahiro Matsuya; Hiroyuki Takamatsu; Yoshihiro Murakami; Akihiro Noda; Kazuhiko 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 224 KB

## Abstract We demonstrated the synthesis of carbon‐11 labeled 17‐__α__‐hydroxy‐11‐__β__‐/4‐/[methyl]‐[1‐methylethyl]‐aminophenyl/‐17__α__‐[prop‐1‐ynyl]esta‐4‐9‐diene‐3‐one (RU40555), a selective glucocorticoid receptor (GR) antagonist, and examined the __in vivo__ profile of [^11^C]RU40555. [^11^