𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and evaluation of 5-HT3 receptor antagonist [11C]KF17643

✍ Scribed by Kiichi Ishiwata; Noriko Saito; Koji Yanagawa; Riko Furuta; Shin-Ichi Ishii; Motohiro Kiyosawa; Yoshio Homma; Kenji Ishii; Fumio Suzuki; Michio Senda

Book ID
116172112
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
670 KB
Volume
23
Category
Article
ISSN
0969-8051

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis and regional rat brain distrib
Synthesis and regional rat brain distribution of [11C]MDL 72222: a 5HT3 receptor antagonist
✍ L. BarrΓ©; D. Debruyne; M.C. Lasne; F. Gourand; G. Bonvento; R. Camsonne; M. Moul πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science βš– 596 KB

MDL 72222, an antagonist of 5HT3 receptors, was labeled with a specific radioactivity of 340-400 mCi/mumol by alkylation of the nor-precursor with [11C]CH3I. The yield of the synthesis, starting from [11C]methyliodide to the purified product and corrected for decay, was good approximately 70-75%. Af

Synthesis and preliminary PET study of t
Synthesis and preliminary PET study of the 5-HT7 receptor antagonist [11C]DR4446
✍ Ming-Rong Zhang; Terushi Haradahira; Jun Maeda; Takashi Okauchi; Takayo Kida; Sh πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 118 KB

DR4446 (1-methyl-2a-[4-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)butyl]-2a, 3,4,5-tetrahydro-1H-benz[cd ]indole-2-one) is a potent 5-HT 7 receptor antagonist (K i ΒΌ 9:7 nM) with a high selectivity over other 5-HT family receptors (K i for 5-HT 1A : 770 nM; for other 5-HT receptors: >1000 nM). As