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Synthesis and in vitro evaluation of galanthamine derivatives for examination of nicotinic acetylcholine receptor system

✍ Scribed by A. Schildan; R. Schirrmacher; M. Samochocki; C. Christner; A. Maelicke; F. Rösch

Book ID
112132894
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
193 KB
Volume
44
Category
Article
ISSN
0022-2135

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## Abstract A new promising galanthamine derivative, 10‐[^3^H]methylgalanthamine iodide, was synthesized for binding studies to nicotinic acetylcholine receptors expressed in Torpedo electric ray electroplaques. Galanthamine was reacted with [^3^H]methyl iodide to yield 10‐[^3^H]methylgalanthamine