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Synthesis and evaluation of new imaging agent for central nicotinic acetylcholine receptor α7 subtype

✍ Scribed by Mikako Ogawa; Shingo Nishiyama; Hideo Tsukada; Kentaro Hatano; Takeshi Fuchigami; Hiroshi Yamaguchi; Yoshitaka Matsushima; Kengo Ito; Yasuhiro Magata

Book ID
116799397
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
937 KB
Volume
37
Category
Article
ISSN
0969-8051

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Synthesis and preliminary evaluation of
Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor
✍ Frédéric Dolle; Héric Valette; Françoise Hinnen; Françoise Vaufrey; Stéphane Dem 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 183 KB

## Abstract The lead compound of a new series of azabicyclic carbamates described by Astra Laboratories as ligands for the __α__7 nicotinic acetylcholine receptor subtype, namely __N__‐(4‐bromophenyl)carbamic acid quinuclidin‐3‐yl ester, has been labelled with carbon‐11 using no‐carrier‐added [^11^