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Synthesis and In Vitro Antibacterial Activity of 7-(3-Alkoxyimino-4-methyl-4-methylaminopiperidin-1-yl)-fluoroquinolone Derivatives

✍ Scribed by Yi-Bin Zhang; Lian-Shun Feng; Xue-Fu You; Qiang Guo; Hui-Yuan Guo; Ming-Liang Liu


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
486 KB
Volume
343
Category
Article
ISSN
0365-6233

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A series of novel 7- (3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3carboxylic acid derivatives was designed, synthesized and characterized by 1 H-NMR, MS and HRMS. These fluoroquinolones were evaluated for their in-vitro antibacterial activity against representat