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Synthesis and in silico drug likeness evaluation of N,5-disubstituted-1,3-thiazolidine-2,4-dione analogues

โœ Scribed by Swathi, Naraparaju; Durai Ananda Kumar, Thirumurthy; Subrahmanyam, Chavali Venkata Satya; Satyanarayana, Kota


Book ID
121526369
Publisher
Elsevier
Year
2013
Tongue
English
Weight
223 KB
Volume
6
Category
Article
ISSN
0974-6943

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## Abstract magnified image 1,5โ€Disubstituted pyrimidineโ€2,4โ€diones were synthesized by fusion of 5โ€bromouracil with an aniline derivative followed by coupling with benzyl halide whereas the opposite synthesis sequence failed. Also 4,6โ€dichloroโ€__N,N__,5โ€trimethylpyrimidinโ€2โ€amine was treated with