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Synthesis and HIV-1 Reverse Transcriptase Inhibitory Activity of Non-Nucleoside Phthalimide Derivatives

✍ Scribed by Jiraporn UNGWITAYATORN; Chanpen WIWAT; Chutima MATAYATSUK; Jutarat PIMTHON; Suratsawadee PIYAVIRIYAKUL


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
197 KB
Volume
26
Category
Article
ISSN
0256-7660

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## Abstract Arylthio isopropyl pyridinylmethylpyrrolemethanols (AThPs) have been recently reported as a new class of human immunodeficiency virus typeβ€…1 (HIV‐1) reverse transcriptase (RT) inhibitors acting at the non‐nucleoside binding site (NNBS) of this enzyme. Docking experiments of the potent i