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Synthesis and evaluation of the antitumor properties of esters of 2-furoic acid and 2-furylacrylic acid

✍ Scribed by Ziaodin Sajadi; Mohammad M. Abrishami; Paricher-Mohseni; James M. Chapman JR.; Iris H. Hall


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
221 KB
Volume
73
Category
Article
ISSN
0022-3549

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The acid-base equilibria of 2-furoic acid hydrazide (FAH) and adipic acid dihydrazide (AADH) were investigated by pH measurements in water-dimethylformamide (10:60, v/v) and water-dioxane (10:60, v/v). The protonation constants were estimated by MINIQUAD which employs a non-linear least squares meth

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## Abstract 2‐Furoic acid was shown to be effective in lowering both serum cholesterol and serum triglyceride levels significantly in rats with an elevation of HDL cholesterol level at 20 mg/kg/day orally. LDL receptor activity was reduced in hepatocytes, aorta foam cells, small intestinal epitheli