Acid—base equilibria of 2-furoic acid hydrazide and adipic acid dihydrazide in aqueous—organic media

✍ Scribed by A.Ravindra Babu; J.S.V.M.Lingeswara Rao; D.Murali Krishna; R.Sambasiva Rao

• Publisher: Elsevier Science
• Year: 1995
• Tongue: English
• Weight: 298 KB
• Volume: 306
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(94)00688-i

✦ Synopsis

The acid-base equilibria of 2-furoic acid hydrazide (FAH) and adipic acid dihydrazide (AADH) were investigated by pH measurements in water-dimethylformamide (10:60, v/v) and water-dioxane (10:60, v/v). The protonation constants were estimated by MINIQUAD which employs a non-linear least squares method based on the Marquardt algorithm. The variation in log Kfl (log poll) and log KY (log PO12 -log poll) for protonation processes against mole fraction were fitted into empirical quadratic models. The number of water molecules released was calculated using a complete equilibrium constant. The stability constants for a few typical systems were compared with SUPERQUAD.