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Synthesis and evaluation of O-(3-[18F]fluoropropyl)-L-tyrosine as an oncologic PET tracer

✍ Scribed by Ganghua Tang; Mingfang Wang; Xiaolan Tang; Lei Luo; Manquan Gan

Book ID
117687984
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
124 KB
Volume
30
Category
Article
ISSN
0969-8051

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## Abstract Two positron‐emitting analogues of tyrosine, __O__‐[^11^C]methyl‐L‐tyrosine and __O__‐[^18^F]fluoromethyl‐L‐tyrosine were prepared as new tumor imaging agents. The alkylating agent, [^11^C]methyl triflate or [^18^F]fluoromethyl triflate, was simply bubbled through a dimethylsulfoxide so