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Evaluation of o-[11C]methyl-L-tyrosine and o-[18F]fluoromethyl-L-tyrosine as tumor imaging tracers by PET

✍ Scribed by Kiichi Ishiwata; Kazunori Kawamura; Wei-Fang Wang; Shozo Furumoto; Kazuo Kubota; Claudio Pascali; Anna Bogni; Ren Iwata

Book ID
116798706
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
270 KB
Volume
31
Category
Article
ISSN
0969-8051

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✍ Ren Iwata; Shozo Furumoto; Claudio Pascali; Anna Bogni; Kiichi Ishiwata πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 140 KB

## Abstract Two positron‐emitting analogues of tyrosine, __O__‐[^11^C]methyl‐L‐tyrosine and __O__‐[^18^F]fluoromethyl‐L‐tyrosine were prepared as new tumor imaging agents. The alkylating agent, [^11^C]methyl triflate or [^18^F]fluoromethyl triflate, was simply bubbled through a dimethylsulfoxide so