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Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase

✍ Scribed by Dajana Gašo-Sokač; Maja Katalinić; Zrinka Kovarik; Valentina Bušić; Spomenka Kovač

Book ID
113518104
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
128 KB
Volume
187
Category
Article
ISSN
0009-2797

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New methods in synthesis of acetylcholin
New methods in synthesis of acetylcholinesterase reactivators and evaluation of their potency to reactivate cyclosarin-inhibited AChE
✍ K. Musílek; L. Lipka; V. Račáková; K. Kuča; D. Jun; V. Dohnal; M. Doležal 📂 Article 📅 2006 🏛 Versita 🌐 English ⚖ 194 KB

## Abstract Nine potential AChE reactivators were synthesized using modification of currently known synthetic pathways. Their potency to reactivate AChE inhibited by cyclosarin nerve agent was tested in vitro. According to the previous results, 1,4-bis(2-hydroxyiminomethylpyridinium)butane dibromid