Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase
β Scribed by McHardy, Stanton F.; Bohmann, Jonathan A.; Corbett, Michael R.; Campos, Bismarck; Tidwell, Michael W.; Thompson, Paul Marty; Bemben, Chris J.; Menchaca, Tony A.; Reeves, Tony E.; Cantrell, William R.; Bauta, William E.; Lopez, Ambrosio; Maxwell, Donald M.; Brecht, Karen M.; Sweeney, Richard E.; McDonough, John
- Book ID
- 121668309
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 621 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0960-894X
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## Abstract Nine potential AChE reactivators were synthesized using modification of currently known synthetic pathways. Their potency to reactivate AChE inhibited by cyclosarin nerve agent was tested in vitro. According to the previous results, 1,4-bis(2-hydroxyiminomethylpyridinium)butane dibromid