Synthesis and Evaluation of Cationic Lipids Bearing Cholesteryl Groups for Gene Delivery in vitro.
β Scribed by Man-Zhou Zhu; Qi-Hua Wu; Guisheng Zhang; Tan Ren; Dexi Liu; Qing-Xiang Guo
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 69 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract In this article, poly(Ξ΅βcaprolactone)βPluronicβpoly(Ξ΅βcaprolactone) (PCFC) copolymer was synthesized by ringβopening polymerization and characterized by ^1^HβNMR and GPC. Cationic PCFC nanoparticles were prepared at oneβstep by modified emulsion solvent evaporation method using cetyltri
The development of new gene delivery technologies is a prerequisite towards gene therapy clinical trials. Because gene delivery mediated by viral vectors remains of limited scope due to immunological and propagation risks, the development of new non-viral gene delivery systems is of crucial importan