𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain

✍ Scribed by Jiyoun Lee; Matthew Bogyo


Book ID
113496516
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
448 KB
Volume
22
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The synthesis and evaluation of peptidyl
✍ Michael D. Mullican; David J. Lauffer; Roger J. Gillespie; Saroop S. Matharu; Da πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 306 KB

The tetrapeptide aldehyde AC-Tyr-Val-Ala-AspH (1, L-709,049) has been reported to be a potent reversible inhibitor of Interleukln-1 B Converting E e (ICE). We have prepared a series of analogs of 1, in order to explore the active site of ICE. The e ects of truncation, methylation of the amide nitrog