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Synthesis and evaluation of anti-proliferative activity of 1,4-disubstituted phthalazines

โœ Scribed by Khaled A. M. Abouzid, Nadia A. Khalil, Eman M. Ahmed


Book ID
118778024
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
348 KB
Volume
21
Category
Article
ISSN
1054-2523

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## Abstract magnified image 1,5โ€Disubstituted pyrimidineโ€2,4โ€diones were synthesized by fusion of 5โ€bromouracil with an aniline derivative followed by coupling with benzyl halide whereas the opposite synthesis sequence failed. Also 4,6โ€dichloroโ€__N,N__,5โ€trimethylpyrimidinโ€2โ€amine was treated with