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Synthesis and Evaluation of a Series of 2′-Deoxy Analogues of The Antiviral Agent 5,6-Dichloro-2-Isopropylamino-1-(β-L-Ribofuranosyl)-1H-Benzimidazole (1263W94)

✍ Scribed by Chan, Joseph H.; Chamberlain, Stanley D.; Biron, Karen K.; Davis, Michelle G.; Harvey, Robert J.; Selleseth, Dean W.; Dornsife, Ronna E.; Dark, Ernest H.; Frick, Lloyd W.; Townsend, Leroy B.; Drach, John C.; Koszalka, George W.


Book ID
121363939
Publisher
Taylor and Francis Group
Year
2000
Tongue
English
Weight
1000 KB
Volume
19
Category
Article
ISSN
0732-8311

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Synthesis and Antiviral Activity of Certain 5'-Modified Analogues of 2, 5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB). -All 18 title compounds, e.g. ( Ib) and (Ic), show significant activity against human cytomegalovirus, some of them similar to lead compound TCRB (Ia), but only little to