Synthesis and evaluation of a novel samarium-153 bifunctional chelating agent for radioimmunotargeting applications
✍ Scribed by Laurence Morandeau; Patricia Remaud-Le Saec; Ali Ouadi; Karine Bultel-Rivière; Marie Mougin-Degraef; Agnès de France-Robert; Alain Faivre-Chauvet; Jean-François Gestin
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- French
- Weight
- 172 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-2135
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📜 SIMILAR VOLUMES
A novel bifunctional chelating agent for actinium was synthesized in eight steps. Bimolecular cyclization between an iminodiester and a polyamine was achieved through the action of a molar equivalent of sodium methoxide.
An Efficient Synthesis of a Novel Bifunctional Chelating Agent. -The first synthesis of an amino-substituted derivative (VIII) of the multidentate ligand 1,2-bis-(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid is achieved. Compound (VIII) may be useful in the development of novel conjugates for r