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Synthesis and evaluation of a macrocyclic bifunctional chelating agent for use with bismuth radionuclides

✍ Scribed by K Garmestani; Z Yao; M Zhang; K Wong; C.W Park; I Pastan; J.A Carrasquillo; M.W Brechbiel


Book ID
117687692
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
205 KB
Volume
28
Category
Article
ISSN
0969-8051

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Evaluation of desferal as a bifunctional
✍ Wilma E. Meijs; Jacobus D.M. Herscheid; Hidde J. Haisma; Herbert M. Pinedo πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science βš– 472 KB

Zirconium-desferal was prepared and analysed by TLC, NMR and u.v.-spectroscopy. The stoichiometry of the complex was found to be 1:1. Chelation of desferal, coupled to resin, with 88Zr appeared to be fast and almost quantitative in various buffer systems in a broad pH-range (4-7). A high in vitro st