Synthesis and Duplex Stabilization of Oligonucleotides Consisting of Isonucleosides
β Scribed by Zhenjun Yang; Huyi Zhang; Jimei Min; Lingtai Ma; Lihe Zhang
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- German
- Weight
- 90 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0018-019X
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Since synthetic oligonucleotides complementary to mRNA sequences were shown to inhibit Rous sarcoma virus replication, [1] oligonucleotide chemists have synthesized all types of analogues to render oligonucleotides suitable as antisense agents. In this context, platinated oligonucleotides have been