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Selective Platination of Modified Oligonucleotides and Duplex Cross-Links

✍ Scribed by Berta Algueró; Jaime López de la Osa; Carlos González; Enrique Pedroso; Vicente Marchán; Anna Grandas

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
108 KB
Volume
45
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.

✦ Synopsis

Since synthetic oligonucleotides complementary to mRNA sequences were shown to inhibit Rous sarcoma virus replication, [1] oligonucleotide chemists have synthesized all types of analogues to render oligonucleotides suitable as antisense agents. In this context, platinated oligonucleotides have been [*] Dr.

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