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Synthesis and conformational study of a cyclic hexapeptide analog of somatostatin containing dehydrophenylalanine

โœ Scribed by Brady, Stephen F. ;Cochran, David W. ;Nutt, Ruth F. ;Holly, Frederick W. ;Bennett, Carl D. ;Paleveda, William J. ;Curley, Paul E. ;Arison, Byron H. ;Saperstein, Richard ;Veber, Daniel F.

Book ID
115098160
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
707 KB
Volume
23
Category
Article
ISSN
0367-8377

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Conformational analyses of cyclic hexape
Conformational analyses of cyclic hexapeptide analogs of somatostatin containing arylalkyl peptoid and naphthylalanine residues
โœ Ralph-Heiko Mattern; Thuy-Anh Tran; Murray Goodman ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB ๐Ÿ‘ 2 views

We report the conformational analysis by 1 H-NMR in DMSO and computer simulations involving distance geometry and molecular dynamics simulations of peptoid analogs of the cyclic hexapeptide c-[Phe 11 -Pro 6 -Phe 7 -D-Trp 8 -Lys 9 -Thr 10 ] L-363,301 (the numbering refers to the positions in native s