## Abstract The stereoselective synthesis of the new nonproteinogenic branched tetrapeptides **9a**β**9d** and **15a**,**b**, containing two Lβvaline units and unnatural __Ξ±__βamino acids, was accomplished starting from the chiral synthon **1a**, a monolactim ether easily obtained from Lβvaline.
Synthesis and conformational preferences of unnatural tetrapeptides containing l-valine units
β Scribed by Daniele Balducci; Andrea Bottoni; Matteo Calvaresi; Gianni Porzi; Sergio Sandri
- Book ID
- 108284166
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 554 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0957-4166
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## Abstract The crystal structure and conformation of the synthetic cyclic tetrapeptide, __cyclo__(LβProβSar)~2~, was determined by xβray analysis. The peptide crystallizes in the orthorhombic space group __P__2~1~2~1~2~1~ with cell parameters __a__ = 9.277(1), __b__ = 12.884(1), and __c__ = 15.581
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