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Stereocontrolled synthesis of unnatural cyclic dipeptides containing an l-valine unit

✍ Scribed by Daniele Balducci; Alessandro Grandi; Gianni Porzi; Sergio Sandri

Book ID
108283933
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
189 KB
Volume
16
Category
Article
ISSN
0957-4166

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πŸ“œ SIMILAR VOLUMES

Stereocontrolled Synthesis of Unnatural
Stereocontrolled Synthesis of Unnatural Tetrapeptides Containing L-Valine Units. Part 3
✍ Daniele Balducci; Gianni Porzi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 German βš– 306 KB

## Abstract The stereoselective synthesis of the new nonproteinogenic branched tetrapeptides **9a**–**9d** and **15a**,**b**, containing two L‐valine units and unnatural __Ξ±__‐amino acids, was accomplished starting from the chiral synthon **1a**, a monolactim ether easily obtained from L‐valine.

Synthesis of a Novel Tricyclic Dipeptide
Synthesis of a Novel Tricyclic Dipeptide Template and Its Incorporation into a Cyclic Peptide Mimetic Containing an NPNA Motif
✍ Marc E. Pfeifer; Anthony Linden; John A. Robinson πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 German βš– 958 KB

A novel tricyclic dipeptide template, formally derived by coupling (2S,4S)-4-aminoproline (Pro(NH,)) and (S)-2-(carboxymethyl)proline (Pro(CH,COOH)) as a diketopiperazine, has been synthesized in a form suitable for solid-phase peptide synthesis using Fmoc chemistry. This ternplate was incorporated