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Synthesis and characterization of μ-conotoxin IIIa

✍ Scribed by Stefan BECKER; Eric ATHERTON; Robert D. GORDON


Book ID
115126497
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
563 KB
Volume
185
Category
Article
ISSN
1432-1327

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## Abstract The 27‐residue polypeptide ω‐conotoxin GVIA (ω‐CgTx), from the venom of the cone shell __Conus geographus__, blocks N‐type neuronal calcium channels. It contains three disulphide bridges. We reporte here the synthesis and biological characterization of a seires of analogues in which one