## Abstract Copper‐catalysed addition of ethyl diazoacetate to methyl scearolate (20 mmol scale) and subsequent saponification gave 9, 10‐carboxymethylene, 9‐octadecenoic acid in 67% yield. The letter was decarbonylated by treatment with HClO~4~/Ac~2~O in the cold (76 μmol scale) to give cycloprope
Synthesis and characterization of [vinylidene-3H] (−)-α-kainic acid at high specific activity
✍ Scribed by David G. Ahern; Richard J. Seguin; Crist N. Filer
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- French
- Weight
- 80 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-2135
- DOI
- 10.1002/jlcr.562
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
[Vinylidene‐^3^H] (−)‐α‐Kainic acid was prepared by means of a Wittig reaction with a protected ketone precursor and has proved useful as a tool to study neuroexcitatory amino acid receptors. Copyright © 2002 John Wiley & Sons, Ltd.
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