Synthesis and characterization of retro gramicidin A-dAla-gramicidin A, a 31-residue-long gramicidin analogue
β Scribed by LELIEVRE, D. ;TRUDELLE, Y. ;HEITZ, F. ;SPACH, G.
- Book ID
- 115098923
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 540 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0367-8377
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π SIMILAR VOLUMES
A new linear gramicidin analog bearing a biotinyl group grafted on C-terminal part was designed to study ligand-receptor interactions. The C-terminal alcohol in the native peptide was first replaced by an amino group. Then the peptide was synthesized on a polystyrene resin functionalized by the 2-ch
## Abstract **Summary:** The controlled polymerisation of a bulky, peptideβbased monomer was investigated. The cyclic __Ξ²__βsheet forming decapeptide gramicidin S was modified with a methacrylate handle and subsequently polymerised via atom transfer radical polymerisation (ATRP), to yield a wellβde