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Chromatographic purification and characterization of synthetic tryptophan-substituted gramicidin A analogues

✍ Scribed by David Salom; Concepción Abad

Book ID
107786087
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
561 KB
Volume
725
Category
Article
ISSN
1873-3778

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Effects of Alanine and Glycine Substitution for Tryptophan on the Heterogeneity of Gramicidin A Analogs in Micelles
✍ J.F. Hinton; A.M. Washburn-McCain; A. Snow; J. Douglas 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 161 KB

The effects of alanine and glycine substitution for tryptophan upon the species heterogeneity of gramicidin A analogs incorporated into SDS micelles have been investigated. The sequential replacement of the four tryptophan residues in gramicidin A at positions 15, 13, 11, and 9 with glycine showed t