✦ LIBER ✦

Synthesis and carcinogenic activity of 5-fluoro-7-(oxygenated methyl)-12-methylbenz[a]anthracenes

✍ Scribed by Newman, Melvin S.; Fikes, Lewis E.; Hashem, Mohamed M.; Kannan, R.; Sankaran, V.

Book ID: 127152844
Publisher: American Chemical Society
Year: 1978
Tongue: English
Weight: 448 KB
Volume: 21
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00208a013

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 12-fluoro-7-methylbenz[a]an

Synthesis of 12-fluoro-7-methylbenz[a]anthracene and 7-fluoro-12-methylbenz[a]anthracene

✍ Newman, Melvin S.; Khanna, J. M. 📂 Article 📅 1979 🏛 American Chemical Society 🌐 English ⚖ 480 KB

Binding of the carcinogens 5-fluoro-7-hy

Binding of the carcinogens 5-fluoro-7-hydroxymethyl-12-methylbenz(a)anthracene and its acetate ester to DNA in vitro

✍ Mu-Tien Chien; James W. Flesher 📂 Article 📅 1981 🏛 Elsevier Science 🌐 English ⚖ 383 KB

Structure and activity in chemical carci

Structure and activity in chemical carcinogenesis: Reactivity and carcinogenicity of 7-bromomethylbenz[a]anthracene and 7-bromomethyl-12-methylbenz[a]anthracene

✍ A. Dipple; T.A. Slade 📂 Article 📅 1970 🏛 Elsevier Science ⚖ 516 KB

Absolute configurations of enantiomeric

Absolute configurations of enantiomeric K-region cis-5,6-dihydrodiols of 12-methylbenz[A] anthracene and 7-bromo-12-methylbenz[A] anthracene

✍ Shen K. Yang; Mohammad Mushtaq; Henri B. Weems; Peter P. Fu 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 266 KB

The absolute configurations of enantiomeric 7-bromo-12lpethylbenz[a]anthracene cis 5,6-dihydrodiols (3) were determined by exciton chirality circular dichroism method, The absolute configurations of enantiomeric 12-methylbenz[a]anthracene c&-5,6-dihydrodiols (1) were determined by debromination of e

Syntheses of Metabolites of 7,12-Dimethy

Syntheses of Metabolites of 7,12-Dimethylbenz[ a ]anthracene. 4-Hydroxy-7,12-dimethylbenz[ a ]anthracene, 7-Hydroxymethyl-12-methylbenz[ a ]anthracene, Their Methyl Ethers, and Acetoxy Derivatives

✍ Flesher, James W.; Soedigdo, Soekeni.; Kelley, Donald R. 📂 Article 📅 1967 🏛 American Chemical Society 🌐 English ⚖ 608 KB

Syntheses of “unstable” diol epoxide met

Syntheses of “unstable” diol epoxide metabolites of the potent carcinogens 7- and 12-methylbenz[a]anthracene

✍ Ronald G. Harvey; Cecilia Cortez; Alexander Kiselyov 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 227 KB

Stereospecific syntheses of the anti-and syn-diol epoxides of 7-and 12-methylbenz[a]anthracene, suspected as active metabolites of the parent PAHs but previously thought to be too chemically reactive and unstable to isolate, are described and the pure compounds are shown to be moderately stable.