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Syntheses of “unstable” diol epoxide metabolites of the potent carcinogens 7- and 12-methylbenz[a]anthracene

✍ Scribed by Ronald G. Harvey; Cecilia Cortez; Alexander Kiselyov

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
227 KB
Volume
7
Category
Article
ISSN
0960-894X

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✦ Synopsis

Stereospecific syntheses of the anti-and syn-diol epoxides of 7-and 12-methylbenz[a]anthracene, suspected as active metabolites of the parent PAHs but previously thought to be too chemically reactive and unstable to isolate, are described and the pure compounds are shown to be moderately stable.

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