Synthesis and biological evaluation of some Schiff bases of 4-amino-5-(4-methylsulfonyl)benzyl-2,4-dihydro-3H-[1,2,4]-triazole-3-thione
✍ Scribed by Sumangala, V.; Poojary, Boja; Chidananda, N.; Arulmoli, T.; Shenoy, Shalini
- Book ID
- 118221710
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- English
- Weight
- 306 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1054-2523
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## Abstract The 4,5‐dihydro‐1,2,4‐triazole Schiff base derivatives were synthesized with 4‐amino‐4,5‐dihydro‐3‐(phenoxy‐ methyl)‐1__H__‐1,2,4‐triazole‐5‐thione and substituted benzaldehydes. The chemical structures of the compounds have been confirmed by ^1^H NMR, IR spectra and elemental analysis.
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The acyclic C=N double bond of the title compound, C~10~H~10~N~4~S, is __trans__ configured. The molecule is almost planar. The angle between the two rings is just 10.25 (7)°. The crystal packing is stabilized by N—H...S hydrogen bonds and π–π interactions.