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Synthesis and Biological Evaluation of S-Neofucopeptides as E- and P-Selectin Inhibitors

✍ Scribed by Antonio J. Moreno-Vargas; Lidia Molina; Ana T. Carmona; Alessandro Ferrali; Martine Lambelet; Olivier Spertini; Inmaculada Robina

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
279 KB
Volume
2008
Category
Article
ISSN
1434-193X

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## Abstract The selectins are a family of cell‐adhesion proteins that mediate the rolling of leukocytes on activated endothelial cells through the recognition of the carbohydrate epitope sialyl Lewis^x^ (sLe^x^). Control of the leukocyte‐endothelial cell adhesion process may prove useful in cases w