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Synthesis and Biological Evaluation of Nitric Oxide-Donating Thalidomide Analogues as Anticancer Agents

✍ Scribed by Tao Wang; Yi-Hua Zhang; Xiang-Wen Kong; Yi-Sheng Lai; Hui Ji; Yan-Ping Chen; Si-Xun Peng

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
186 KB
Volume
6
Category
Article
ISSN
1612-1872

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## Abstract In order to evaluate the anti‐hyperlipidemic effect of synthetic chalcones and some analogues, nineteen compounds with different substituents in both rings were synthesized and hypolipidemic activities were measured __in vivo__ using Triton WR1339 acute and hypercaloric chronic assays.