𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Biological Evaluation of Gephyronic Acid Derivatives: Initial Steps towards the Identification of the Biological Target of Polyketide Inhibitors of Eukaryotic Protein Synthesis

✍ Scribed by Timo Anderl; Lionel Nicolas; Johanna Münkemer; Yazh Muthukumar; Angelika Baro; Wolfgang Frey; Florenz Sasse; Richard E. Taylor; Sabine Laschat


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
1014 KB
Volume
2011
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Total Synthesis and Biological Evaluatio
✍ Laurent Bialy; Herbert Waldmann 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 481 KB 👁 2 views

## Abstract The total synthesis of the natural product cytostatin is described which inhibits protein phosphatase 2A. Cytostatin has anti‐metastatic properties and induces apoptosis. On the basis of this synthesis the relative and absolute configuration of cytostatin could be assigned. Key structur

ChemInform Abstract: Synthesis and Biolo
✍ Tsutomu Yokomatsu; Tetsuo Murano; Ikuko Umesue; Shinji Soeda; Hiroshi Shimeno; S 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Synthesis and Biological Evaluation of α,α-Difluorobenzylphosphonic Acid Derivatives as Small Molecular Inhibitors of Protein-Tyrosine Phosphatase 1B. -Title compounds (V) and (XI) are prepared by a Stille coupling reaction sequence. It is shown that desired inhibitory activity towards protein-tyro

Synthesis and Biological Evaluation of N
✍ Olivier Lavergne; Anne-Cecile Fernandes; Laetitia Brehu; Alban Sidhu; Marie-Chri 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 42 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Synthesis and Biological Evaluation of P
✍ Farid El Oualid; Leon Bruining; Ingrid M. Leroy; Louis H. Cohen; Jacques H. van  📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 244 KB 👁 2 views

Dedicated to Professor Dieter Seebach on the occasion of his 65th birthday Two orthogonally protected SAA building blocks were used in the synthesis of eight novel analogues of the CaaX motif present in the natural substrates of protein:geranylgeranyltransferase I (PGGT I), an enzyme involved in the