## Abstract ^123^I‐iodophenylpentadecanoic acid (IPPA) and ^123^I‐beta‐methyliodophenylpentadecanoic acid (BMIPP) are radiolabelled fatty acid derivatives used for assessment of myocardial viability. Because of limited accessibility of ^123^I in the clinical scenario, a 99m‐technetium‐based agent w
Synthesis and biological evaluation of a technetium-99m(I)-tricarbonyl-labelled phenyltropane derivative
✍ Scribed by Davy M. Kieffer; Bernard J. Cleynhens; Hubert P. Vanbilloen; Dirk Rattat; Christelle Y. Terwinghe; Luc Mortelmans; Guy M. Bormans; Alfons M. Verbruggen
- Book ID
- 108073825
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 128 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0960-894X
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## Abstract Biological and chemical characteristics of ^99m^Tc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these ^99m^Tc‐complex
## Abstract The synthesis of a novel technetium‐99m labelled derivative of L‐tyrosine as a potential tumour imaging agent for nuclear medicine diagnosis is reported. The synthesis involved the labelling precursor __fac__‐[^99m^Tc(OH~2~)(CO)~3~]^+^ which was synthesized using the commercially availa