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Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue

✍ Scribed by Karl Gademann; Martin Ernst; Daniel Hoyer; Dieter Seebach


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
132 KB
Volume
38
Category
Article
ISSN
0044-8249

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✍ Andreas F. Petri; Florenz Sasse; Martin E. Maier 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 2 views

## Abstract Reactions between amide anions and propanal derivatives containing benzolactone components at their 3‐positions produced hemiaminals, which were dehydrated via the corresponding acetates to provide the apicularen A analogues **21**, **29**, **34**, **38**, and **41**. Of these, **21** a