## Abstract An expeditious total synthesis of the highly cytotoxic F‐ATPase inhibitor cruentaren A (**1**) is described based on a ring‐closing alkyne metathesis (RCAM) reaction for the formation of the macrocylic ring. Other key transformations comprise a C‐acylation of the benzyl lithium reagent
✦ LIBER ✦
Synthesis and Biological Evaluation of Cruentaren A Analogues
✍ Scribed by Viktor V. Vintonyak; Marcellino Calà; Frank Lay; Brigitte Kunze; Florenz Sasse; Martin E. Maier
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 415 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0947-6539
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