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Synthesis and Biological Evaluation of (-)-16-Normethyldictyostatin: A Potent Analogue of (-)-Dictyostatin.

✍ Scribed by Youseung Shin; Jean-Hugues Fournier; Raghavan Balachandran; Charitha Madiraju; Brianne S. Raccor; Guangyu Zhu; Michael C. Edler; Ernest Hamel; Billy W. Day; Dennis P. Curran


Publisher
John Wiley and Sons
Year
2005
Weight
12 KB
Volume
36
Category
Article
ISSN
0931-7597

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Abstract

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✍ Andreas F. Petri; Florenz Sasse; Martin E. Maier πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 194 KB πŸ‘ 2 views

## Abstract Reactions between amide anions and propanal derivatives containing benzolactone components at their 3‐positions produced hemiaminals, which were dehydrated via the corresponding acetates to provide the apicularen A analogues **21**, **29**, **34**, **38**, and **41**. Of these, **21** a