𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and biological evaluation of 5,6-diarylimidazo[2.1-b]thiazole as selective COX-2 inhibitors

✍ Scribed by Michel Thérien; Christine Brideau; Chi Chung Chan; Wanda A. Cromlish; Jacques Yves Gauthier; Robert Gordon; Gillian Greig; Stacia Kargman; Cheuk Kun Lau; Yves Leblanc; Chun-Sing Li; Gary P. O'Neill; Denis Riendeau; Patrick Roy; Zhaoyin Wang; Lijing Xu; Petpiboon Prasit

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
270 KB
Volume
7
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.

✦ Synopsis

A series of 5,6-diarylimidazo[2.1-b]thiazole compounds were prepared and their inhibitory potencies against COX-2 and Cox-1 enzymes were measured. This led to the identification of L-766,112 as a potent, orally active and selective inhibitor of the COX-2 enzyme.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis and Biolo
ChemInform Abstract: Synthesis and Biological Evaluation of 5,6-Diarylimidazo(2.1-b) thiazole as Selective COX-2 Inhibitors.
✍ M. THERIEN; C. BRIDEAU; C. C. CHAN; W. A. CROMLISH; J. Y. GAUTHIER; R. GORDON; G 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v